PMH47 THE MISSION IS REMISSION–HEALTH ECONOMIC CONSEQUENCES OF ACHIEVING REMISSION WITH ANTIDEPRESSANT TREATMENT FOR DEPRESSION

Towards achieving remission in the treatment of depression

The burden of depressive illness constitutes a major public health issue. Despite real progress and better tolerance of new antidepressant medications, a significant number of depressed patients still suffer from rather severe residual depressive symptoms.This relative lack of efficacy clearly interferes with their psychosocial functioning and their quality of life. In addition, it is now well-...

When is antidepressant polypharmacy appropriate in the treatment of depression?

Depression is a serious medical condition that is often only partially improved or completely unchanged after standard treatment with antidepressant medications. Various approaches have been developed to treat this subgroup of individuals with 'treatment-resistant' depression; but many individuals continue to live with chronic depressive symptoms that seriously affect their quality of life and ...

The human cost of not achieving full remission in depression.

Depression is among the most disabling and costly illnesses in the world. Despite good short-term efficacy outcomes in the treatment of depression, long-term outcomes remain disappointing. Depression continues to be missed or underdiagnosed and undertreated, and comorbidities are frequently not identified. Of particular concern is the low rate of depression treated to full remission. Treating o...

Treatment of childhood depression with antidepressant drugs.

Predicting antidepressant treatment without controlling for depression is ill-advised.

Madsen et al. (2015) examined the prospective association between work-related burnout and antidepressant treatment in human service workers. The authors defined work-related burnout based on exhaustion symptoms assessed in the occupational context. They concluded that work-related burnout is an important risk factor for antidepressant treatment. While we read the authors' article with interest...